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Critical care, including ICU-sedation and patient-centered management of pain, agitation and delirium, is one of the key expertise areas of Orion Pharma.
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About dexdor (dexmedetomidine)
Dexdor (dexmedetomidine) is indicated to use for sedation of adult Intensive Care Unit patients requiring a sedation level not deeper than arousal in response to verbal stimulation (corresponding to Richmond Agitation-Sedation Scale (RASS) 0 to -3).
Dexdor (dexmedetomidine) is contraindicated in hypersensitivity to the active substance or to any of the excipients, in advanced heart block (grade 2 or 3) unless paced, in uncontrolled hypotension, in acute cerebrovascular conditions.
Dexdor (dexmedetomidine) is for hospital use only, it should be administered by healthcare professionals skilled in the management of patients requiring intensive care.
Reference information, dexdor (dexmedetomidine)
Link to the Summary of Product Characteristics and to the Package leaflet: Information for the user, Dexdor (dexmedetomidine)
Link to the European Public Assessment Report, Dexdor (dexmedetomidine)
Dexmedetomidine in adult ICU
Sedation effects by dexmedetomidine versus propofol in decreasing duration of mechanical ventilation after open heart surgery.Elgebaly AS, Sabry M
Ann Card Anaesth
Comparison of dexmedetomidine versus propofol on hemodynamics in surgical critically ill patients.Chang YF, Chao A, Shih PY, Hsu YC, Lee CT, Tien YW, Yeh YC, Chen LW, NTUH Center of Microcirculation Medical Research (NCMMR).
J Surg Res
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.Nunes SL, Forsberg S, Blomqvist H, Berggren L, Sörberg M, Sarapohja T, Wickerts CJ
Clin Drug Investig